Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Alcohol plays a major role in criminal activity, particularly violent offences. Government data suggests that nearly 40% of violent crimes involve alcohol consumption.
The Sinclair Method (TSM) offers a compassionate, scientifically-backed alternative to traditional abstinence-based approaches for treating Alcohol Use Disorder (AUD). By utilising the opioid antagonist naltrexone, TSM enables individuals to gradually reduce their alcohol consumption, leading to significant benefits both physically and emotionally.
For individuals looking to reduce or stop drinking, withdrawal symptoms can be a significant challenge. In the UK, doctors commonly prescribe Librium (Chlordiazepoxide) and Diazepam to manage withdrawal. However, a growing number of experts advocate for gradual reduction with Naltrexone as a safer and more sustainable approach.
Alcohol dependency can feel overwhelming, but it’s essential to know that effective, science-backed treatments exist today. One of the most successful methods is The Sinclair Method (TSM)—a medically supported approach that boasts a 78% success rate in helping people reduce their alcohol consumption and regain control.
Every year, thousands of people take on Dry January, pledging to stay alcohol-free for a month. The idea is simple: give your body a break, improve your health, and prove to yourself that you can go without alcohol. While the benefits—like better sleep, weight loss, and financial savings—sound appealing, the long-term effects of temporary abstinence aren’t always positive.
When we consume alcohol, it interacts with our brain's complex reward system. Specifically, alcohol triggers the release of endorphins, chemicals that produce feelings of pleasure and relaxation. These endorphins bind to opioid receptors in the brain, reinforcing drinking behaviours and making alcohol consumption feel rewarding.